Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621948 | 0.98 | TDP1 (0.63) | TDP1CES1CA1CA2CES2 | |
| Thiobenzoic Acid SCHEMBL7584058 | 0.86 | CES1 (0.59) | TDP1CES1CA1CA2CES2 | |
| Hydrogen Peroxide SCHEMBL28789390 | 0.83 | ALDH1A1 (0.72) | TDP1CES1CA1CA2CES2 | |
| 4-Nitrotoluene SCHEMBL23112224 | 0.82 | ACHE (0.60) | TDP1CES1CES2ALDH1A1MAPK1 | |
| Thiobenzoic Acid SCHEMBL8579917 | 0.82 | CES2 (0.54) | TDP1CES1CES2ALDH1A1MAPK1 | |
| SCHEMBL875011 | 0.80 | CES1 (0.59) | TDP1CES1CA1CA2CES2 | |
| SCHEMBL6736177 | 0.80 | ALDH1A1 (0.67) | TDP1CES1CA1CA2CES2 | |
| SCHEMBL874833 | 0.80 | TSHR (0.67) | TDP1CES1CA1CA2CES2 | |
| Potassium Ion SCHEMBL10621944 | 0.80 | CA1 (0.63) | TDP1CES1CA1CA2CES2 | |
| 4-Nitrotoluene SCHEMBL21633328 | 0.79 | ACHE (0.51) | TDP1CES1CES2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252814-A | ANTIFERTILITY AGENTS, INSECTICIDES | AMERICAN CYANAMID COMPANY (US) | 1981-02-24 | — | — | US | claimed |
| EP-4320124-A1 | DICHALCOGENIDE PRODRUGS | Ludwig-Maximilians-Universität München (DE) | 2024-02-14 | — | — | EP | disclosed |
| EP-4313156-A1 | DISULFIDE-BASED PRODRUG COMPOUNDS | Ludwig-Maximilians-Universität München (DE) | 2024-02-07 | — | — | EP | disclosed |
| CN-114478149-B | Carboxylic acid compound and preparation method thereof | 吉林化工学院 | 2023-09-15 | — | — | CN | disclosed |
| WO-2022214598-A1 | DICHALCOGENIDE PRODRUGS | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2022-10-13 | — | — | WO | disclosed |
| WO-2022200347-A1 | DISULFIDE-BASED PRODRUG COMPOUNDS | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2022-09-29 | — | — | WO | disclosed |
| CN-114478149-A | Carboxylic acid compound and preparation method thereof | 吉林化工学院 | 2022-05-13 | — | — | CN | disclosed |
| CN-107793388-B | Platemycin analogue and preparation method and application thereof | 长沙天赐生物医药科技有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-20020151089-A1 | Separating components of biological samples | MIRAIBIO, INC. | 2002-10-17 | — | — | US | disclosed |
| US-4771068-A | Mitomycin derivatives having anti-tumor and antibacterial utility | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4275184-A | HYDROSILATION OF POLYDIMETHYL SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1981-06-23 | — | — | US | disclosed |
| US-4213914-A | ADDITION-CONDENSATION COPOLYMERS | RHONE-POULENC INDUSTRIES (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4119717-A | STEROIDS, ANTIMICROBIAL AGENTS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1978-10-10 | — | — | US | disclosed |
| US-4088670-A | P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID | RHONE-POULENC INDUSTRIES (FR) | 1978-05-09 | — | — | US | disclosed |