Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967499 | 0.87 | CHRM2 (0.45) | CHRM2CHRM3OPRD1OPRK1 | |
| SCHEMBL6970176 | 0.80 | OPRD1 (0.45) | CHRM2CHRM3OPRD1OPRK1 | |
| SCHEMBL6965179 | 0.79 | OPRD1 (0.50) | CHRM2CHRM3MEN1KMT2AOPRD1 | |
| SCHEMBL6968136 | 0.79 | OPRD1 (0.44) | CHRM2CHRM3OPRD1OPRK1 | |
| SCHEMBL6974605 | 0.78 | OPRD1 (0.44) | OPRD1OPRK1 | |
| SCHEMBL6970267 | 0.76 | POLB (0.46) | MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL6965660 | 0.76 | CHRM4 (0.43) | CHRM2CHRM3OPRD1OPRK1 | |
| SCHEMBL6972934 | 0.75 | PKM (0.45) | OPRD1OPRK1 | |
| SCHEMBL6981816 | 0.75 | OPRD1 (0.48) | OPRD1OPRK1 | |
| SCHEMBL6977389 | 0.74 | OPRD1 (0.44) | OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-A1 | NOVEL DIPHENYL-PIPERIDINE DERIVATE | AstraZeneca UK Limited (GB) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001005782-A1 | NOVEL DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LIMITED (GB) | 2001-01-25 | — | — | WO | disclosed |