SCHEMBL752074

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8996690	1.00	TSHR (0.37)	TSHRCA12CA1CA2CA9
	SCHEMBL8996619	1.00	TSHR (0.37)	TSHRCA12CA1CA2CA9
	SCHEMBL20022609	0.89	TSHR (0.42)	TSHRCA12CA1CA2CA9
	SCHEMBL25475997	0.86	TSHR (0.33)	TSHRHSD17B10MGAMGAASI
	SCHEMBL2580362	0.84	TSHR (0.44)	TSHRCA12CA1CA2CA9
	SCHEMBL2580366	0.84	TSHR (0.44)	TSHRCA12CA1CA2CA9
	SCHEMBL14969737	0.83	ALDH1A1 (0.37)	TSHRHSD17B10MGAMGAASI
	SCHEMBL19090746	0.82	BIRC2 (0.38)	TSHRCA12CA1CA2CA9
	SCHEMBL14591443	0.82	CA1 (0.37)	TSHRCA12CA1CA2CA9
	SCHEMBL20988042	0.80	BIRC2 (0.39)	TSHRCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.