Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | PDE6D | O43924 | 2/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520505 | 0.88 | KCNH2 (0.65) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL7512243 | 0.85 | BRD4 (0.60) | KMT2AGAAMGAMSIMGAM2 | |
| SCHEMBL7512060 | 0.82 | RHEB (0.56) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL7511275 | 0.82 | KCNH2 (0.53) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL7510191 | 0.82 | MGAM (0.82) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL7512735 | 0.82 | MGAM (0.82) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| Benzaldehyde SCHEMBL28311657 | 0.82 | ALDH1A1 (0.78) | ALDH1A1PDE6DALDH2ALDH3A1GAA | |
| SCHEMBL8021682 | 0.80 | TP53 (0.77) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL28261637 | 0.77 | ALDH1A1 (0.91) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL3969688 | 0.76 | TNF (0.70) | KMT2AALDH1A1PDE6DALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452014-B1 | THIAZOLIDINEDIONE COMPOUNDS | GERON CORPORATION | 2002-09-17 | — | — | US | disclosed |
| US-20020120144-A1 | Telomerase inhibitors and methods of their use | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-08-29 | — | — | US | disclosed |
| WO-2002051409-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120144-A1 | Telomerase inhibitors and methods of their use | TERT, TERF2, POT1 | KMT2A 1503/4885ALDH1A1 786/4885PDE6D 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.