SCHEMBL752089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19591020	0.83	GRM4 (0.43)	GRM4ALDH1A1NOS2POLBGAA
	SCHEMBL9096133	0.78	KCNH2 (0.57)	KCNH2NOS1GRM4DHFRBACE1
	SCHEMBL17898217	0.78	KCNH2 (0.57)	KCNH2NOS1DHFRKDM4EALDH1A1
	SCHEMBL990352	0.77	KCNH2 (0.52)	KCNH2NOS1ALDH1A1BACE1CYP1A2
	SCHEMBL805512	0.76	KDM4E (0.42)	KCNH2NOS1GRM4KDM4EALDH1A1
	SCHEMBL12206982	0.75	KCNH2 (0.49)	KCNH2NOS1DHFRKDM4EALDH1A1
	SCHEMBL28257410	0.74	KCNH2 (0.52)	KCNH2NOS1KDM4EALDH1A1HPGD
	SCHEMBL1207127	0.74	NOS2 (0.51)	KCNH2NOS1KDM4EALDH1A1HPGD
	SCHEMBL12153420	0.74	—	—
	SCHEMBL17898214	0.74	KCNH2 (0.52)	KCNH2NOS1DHFRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.