Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 8/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072486 | 0.88 | KCNH2 (0.47) | KDM4ELMNACYP3A4TSHRNOS2 | |
| SCHEMBL11561943 | 0.86 | KCNH2 (0.55) | KDM4ENOS2L3MBTL1ALDH1A1KCNH2 | |
| SCHEMBL17053275 | 0.84 | KCNH2 (0.58) | KDM4ELMNACYP3A4NOS2L3MBTL1 | |
| SCHEMBL22298878 | 0.84 | KCNH2 (0.58) | KDM4ELMNACYP3A4NOS2L3MBTL1 | |
| SCHEMBL30481675 | 0.82 | — | — | |
| SCHEMBL805491 | 0.82 | — | — | |
| SCHEMBL12831941 | 0.79 | GRM4 (0.31) | GRM4 | |
| SCHEMBL27592765 | 0.78 | KDM4E (0.42) | KDM4ELMNACYP3A4TSHRNOS2 | |
| SCHEMBL2262446 | 0.78 | KDM4E (0.33) | KDM4ELMNANOS2MAPTALDH1A1 | |
| SCHEMBL10468472 | 0.77 | KDM4E (0.44) | KDM4ELMNACYP3A4TSHRNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| WO-2023150394-A1 | METHODS FOR TREATMENT OF CANCER | FRONTIER MEDICINES CORPORATION (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2018-02-01 | — | — | US | disclosed |
| EP-3265447-A1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | Huntsman Advanced Materials Americas LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-20160194303-A1 | HETEROCYCLES CAPABLE OF MODULATING T-CELL RESPONSES, AND METHODS OF USING SAME | NOGRA PHARMA LIMITED (IE) | 2016-07-07 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20080146569-A1 | Nicotinamide Derivatives | PFIZER INC. | 2008-06-19 | — | — | US | disclosed |
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-0328020-B1 | Use of a catalyst in epoxy compositions | DOW CHEMICAL CO (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5503937-A | MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE | THE DOW CHEMICAL COMPANY (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0553887-A2 | Catalysts and epoxy resin composition containing the same | THE DOW CHEMICAL COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5134239-A | Quaterinary indolizine compound | THE DOW CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194303-A1 | HETEROCYCLES CAPABLE OF MODULATING T-CELL RESPONSES, AND METHODS OF USING SAME | ICOS, NFATC1, CD74 | KDM4E 1996/4885LMNA 4845/4885CYP3A4 1012/4885 |
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | CRYZ, PIEZO1, PSMD12 | KDM4E 471/4885LMNA 1771/4885CYP3A4 1284/4885 |
| US-20080146569-A1 | Nicotinamide Derivatives | NNT, NAMPT, NADK | KDM4E 3026/4885LMNA 1093/4885CYP3A4 315/4885 |
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | KDM4E 2727/4885LMNA 1463/4885CYP3A4 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.