Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051227 | 1.00 | JUN (0.39) | JUNNFKB1ALOX5HDAC1HDAC6 | |
| SCHEMBL15195462 | 0.82 | CYP1A2 (0.41) | HDAC1HDAC6MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7521388 | 0.82 | CYP1A2 (0.41) | HDAC1HDAC6MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7521391 | 0.82 | CYP1A2 (0.41) | HDAC1HDAC6MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7052809 | 0.81 | CYP11B1 (0.46) | JUNNFKB1ALOX5NPC1MAPT | |
| SCHEMBL7523335 | 0.81 | CYP11B1 (0.46) | JUNNFKB1ALOX5NPC1MAPT | |
| SCHEMBL7054847 | 0.73 | JUN (0.38) | JUNNFKB1ALOX5HDAC1HDAC6 | |
| SCHEMBL7522228 | 0.73 | JUN (0.38) | JUNNFKB1ALOX5HDAC1HDAC6 | |
| SCHEMBL7515532 | 0.68 | HDAC8 (0.38) | NFKB1CYP1A2ALOX15KDM4ECYP3A4 | |
| SCHEMBL23639908 | 0.67 | NPC1 (0.41) | JUNNFKB1ALOX5NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | disclosed |