Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523335 | 1.00 | CYP11B1 (0.46) | CYP11B1CYP11B2MAPTRAB9ANPC1 | |
| SCHEMBL7051227 | 0.81 | JUN (0.39) | CYP11B2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL7520907 | 0.81 | JUN (0.39) | CYP11B2MAPTRAB9ANPC1KDM4E | |
| SCHEMBL7521391 | 0.80 | CYP1A2 (0.41) | MAPTKMT2AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL7521388 | 0.80 | CYP1A2 (0.41) | MAPTKMT2AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL15195462 | 0.80 | CYP1A2 (0.41) | MAPTKMT2AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL10193817 | 0.77 | ALOX5 (0.55) | CYP11B1CYP11B2MAPTRAB9ANPC1 | |
| SCHEMBL7522335 | 0.76 | MAPT (0.43) | CYP11B1CYP11B2MAPTRAB9ANPC1 | |
| SCHEMBL7522328 | 0.76 | MAPT (0.43) | CYP11B1CYP11B2MAPTRAB9ANPC1 | |
| SCHEMBL6450540 | 0.71 | CHRNB2 (0.53) | CYP11B1CYP11B2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303615-A2 | FERMENTATION PROCESS FOR EPOTHILONES | Kosan Biosciences, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | disclosed |
| WO-2002008440-A2 | FERMENTATION PROCESS FOR EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2002-01-31 | — | — | WO | disclosed |