Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521388 | 1.00 | CYP1A2 (0.41) | CYP1A2CNR2CYP3A4ALDH1A1MAOB | |
| SCHEMBL15195462 | 1.00 | CYP1A2 (0.41) | CYP1A2CNR2CYP3A4ALDH1A1MAOB | |
| SCHEMBL7520907 | 0.82 | JUN (0.39) | CYP1A2CYP3A4ALDH1A1MAPTHDAC3 | |
| SCHEMBL7051227 | 0.82 | JUN (0.39) | CYP1A2CYP3A4ALDH1A1MAPTHDAC3 | |
| SCHEMBL7052809 | 0.80 | CYP11B1 (0.46) | CYP1A2CYP3A4ALDH1A1MAPTCYP2D6 | |
| SCHEMBL7523335 | 0.80 | CYP11B1 (0.46) | CYP1A2CYP3A4ALDH1A1MAPTCYP2D6 | |
| SCHEMBL1853495 | 0.76 | CYP1A2 (0.46) | CYP1A2CNR2CYP3A4ALDH1A1MAOB | |
| SCHEMBL1853494 | 0.76 | CYP1A2 (0.46) | CYP1A2CNR2CYP3A4ALDH1A1MAOB | |
| SCHEMBL11197059 | 0.75 | CYP1A2 (0.44) | CYP1A2CNR2CYP3A4ALDH1A1MAOB | |
| SCHEMBL9997586 | 0.75 | CYP1A2 (0.44) | CYP1A2CNR2CYP3A4ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137152-A1 | Fermentation process for epothilones | KOSAN BIOSCIENCES, INC. | 2002-09-26 | — | — | US | disclosed |