SCHEMBL7520962

SCHEMBL7520962

C=C(CC(O)Cc1ccccc1-c1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.57
FOLH1 Q04609 1/20 0.40
MME P08473 1/20 0.40
ACE P12821 1/20 0.40
CPA1 P15085 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
DPP4 P27487 1/20 0.40
KCNA5 P22460 2/20 0.39
KCNH2 Q12809 1/20 0.39
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP12 P39900 1/20 0.38
MMP13 P45452 1/20 0.38
MMP14 P50281 1/20 0.38
PTGER1 P34995 2/20 0.37
PTGER4 P35408 2/20 0.37
PTGER3 P43115 2/20 0.37
PTGER2 P43116 2/20 0.37
TET2 Q6N021 3/20 0.37
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379631 0.84 KMT2A (0.64) KMT2AFOLH1MMEACECPA1
SCHEMBL10015434 0.80 KMT2A (0.66) KMT2AFOLH1MMEACECPA1
SCHEMBL28463444 0.78 KMT2A (0.60) KMT2AFOLH1MMEACECPA1
SCHEMBL867318 0.77 KMT2A (0.53) KMT2AFOLH1DPP4PTGER1PTGER4
SCHEMBL4453375 0.77 TRPA1 (0.57) FOLH1CPA1TET2TET3TET1
SCHEMBL29358263 0.77 KMT2A (0.53) KMT2AFOLH1DPP4PTGER1PTGER4
SCHEMBL1535473 0.75 ALDH1A1 (0.54) KMT2A
SCHEMBL15732948 0.74 PTGER4 (0.55) KMT2AFOLH1DPP4PTGER1PTGER4
SCHEMBL2865284 0.74 KMT2A (0.58) KMT2AFOLH1MMEACECPA1
SCHEMBL13212054 0.74 KMT2A (0.58) KMT2AFOLH1MMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735062-B1 ACTINIC-RADIATION-CURABLE COMPOSITION AND LENS SHEET MITSUBISHI RAYON CO (JP) 2002-01-30 EP claimed