SCHEMBL7520992

SCHEMBL7520992

Brc1ccc(-c2cccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.47
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
HTR7 P34969 1/20 0.39
HTR2B P41595 1/20 0.39
PRCP P42785 1/20 0.38
MAOA P21397 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
PTPRC P08575 1/20 0.36
SLC6A3 Q01959 1/20 0.36
TDP2 O95551 1/20 0.36
KDR P35968 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
ANPEP P15144 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28928665 0.85 PNMT (0.50) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27983232 0.84 PGR (0.40) PNMTNPC1RAB9AALDH1A1MAPK1
SCHEMBL29809707 0.84 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29401802 0.84 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL70992 0.84 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27707634 0.84 L3MBTL1 (0.45) PNMTALDH1A1MAPK1HTR7PRCP
SCHEMBL3553779 0.84 PNMT (0.46) PNMTNPC1RAB9AALDH1A1HTR7
Bromide SCHEMBL15404509 0.82 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27718430 0.82 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL28013095 0.82 PNMT (0.45) PNMTNPC1RAB9AALDH1A1HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894558-A Aromatic phosphine oxide compound containing diphenylfluorene and preparation method thereof 黑龙江大学 2023-04-04 CN claimed
CN-103864845-B Quaternary big conjugation aromatic phosphines oxygen material of main part and synthetic method thereof 黑龙江大学 2016-08-17 CN claimed
CN-103012098-B Derivative of fluorenes and preparation method thereof EAST CHINA NORMAL UNIVERSITY (CN) 2016-02-03 CN claimed
CN-103012098-A Fluorene derivative and preparation method thereof UNIV EAST CHINA NORMAL 2013-04-03 CN claimed
CN-118276407-A Photosensitive resin composition, cured film, and black matrix 新应材股份有限公司 2024-07-02 CN disclosed
CN-117369211-A Resin composition, cured film, and color filter 新应材股份有限公司 2024-01-09 CN disclosed
CN-115894558-A Aromatic phosphine oxide compound containing diphenylfluorene and preparation method thereof 黑龙江大学 2023-04-04 CN disclosed
CN-108883983-B Intermediate film for laminated glass 株式会社可乐丽 2022-02-01 CN disclosed
CN-112552286-B Nitrogen-containing compound, electronic element comprising same and electronic device 陕西莱特迈思光电材料有限公司 2021-11-16 CN disclosed
CN-112552286-A Nitrogen-containing compound, electronic element comprising same and electronic device 陕西莱特迈思光电材料有限公司 2021-03-26 CN disclosed
CN-103864845-B Quaternary big conjugation aromatic phosphines oxygen material of main part and synthetic method thereof 黑龙江大学 2016-08-17 CN disclosed
CN-103012098-B Derivative of fluorenes and preparation method thereof EAST CHINA NORMAL UNIVERSITY (CN) 2016-02-03 CN disclosed
CN-103012098-A Fluorene derivative and preparation method thereof UNIV EAST CHINA NORMAL 2013-04-03 CN disclosed
WO-2002004543-A1 COPOLYMER SEMI-CONDUCTOR MATERIALS MADE OF OLIGO-PHENYLENE UNITS AND AT LEAST ONE FLUORENE UNIT SIEMENS AKTIENGESELLSCHAFT (DE) 2002-01-17 WO disclosed
WO-2001056091-A2 CHARGE TRANSPORT MATERIAL HAVING AN INCREASED GLASS TRANSITION TEMPERATURE AND THE USE OF SAID MATERIAL SIEMENS AKTIENGESELLSCHAFT (DE) 2001-08-02 WO disclosed