Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861457 | 0.98 | CRHBP (0.47) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL6037684 | 0.98 | CRHBP (0.47) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL27413653 | 0.91 | CRHBP (0.51) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL28833591 | 0.88 | CRHBP (0.49) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL27333858 | 0.86 | HDAC3 (0.49) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL27702248 | 0.86 | CRHBP (0.48) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL27716236 | 0.86 | HDAC3 (0.49) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL32684616 | 0.85 | CRHBP (0.56) | CRHBPCRHR2ESR1ESR2ALDH1A1 | |
| SCHEMBL11043165 | 0.85 | CRHBP (0.47) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL9261002 | 0.85 | MGLL (0.47) | CRHBPCRHR2ESR1ESR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630899-B1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND MEDICINE CONTAINING THE SAME | OTSUKA KAGAKU KK (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5635500-A | EFFECTIVE IN TREATING INFECTIOUS DISEASES ASSOCIATED WITH METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0630899-A1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND MEDICINE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1994-12-28 | — | — | EP | disclosed |