Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861457 | 1.00 | CRHBP (0.47) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL7521589 | 0.98 | CRHBP (0.48) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL27413653 | 0.93 | CRHBP (0.51) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL27333858 | 0.88 | HDAC3 (0.49) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL27716236 | 0.88 | HDAC3 (0.49) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL9261002 | 0.87 | MGLL (0.47) | CRHBPCRHR2ESR1ESR2LPAR1 | |
| SCHEMBL28833591 | 0.86 | CRHBP (0.49) | CRHBPCRHR2ESR1ESR2MGLL | |
| SCHEMBL4214175 | 0.85 | LMNA (0.54) | CRHBPCRHR2LMNAMAPTALDH1A1 | |
| SCHEMBL964635 | 0.85 | LMNA (0.54) | CRHBPCRHR2LMNAMAPTALDH1A1 | |
| SCHEMBL966036 | 0.85 | LMNA (0.54) | CRHBPCRHR2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060216761-A1 | Isolation material for hormone disrupting substance, method of concentrating and method of clean-up | JAPAN ENVIROCHEMICALS, LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| EP-1514597-A1 | ISOLATION MATERIAL FOR HORMONE DISRUPTING SUBSTANCE, METHOD OF CONCENTRATING AND METHOD OF CLEAN-UP | Japan Envirochemicals, Ltd. (JP) | 2005-03-16 | — | — | EP | disclosed |