Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521700 | 1.00 | TRPA1 (0.39) | TRPA1HRH1LMNASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7922158 | 0.98 | TRPA1 (0.38) | TRPA1HRH1LMNASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7922157 | 0.98 | TRPA1 (0.38) | TRPA1HRH1LMNASLC6A2SLC6A4 | |
| SCHEMBL5282777 | 0.78 | LMNA (0.45) | TRPA1HRH1LMNATAAR1HTR2A | |
| SCHEMBL11655728 | 0.74 | CYP2C19 (0.46) | TAAR1HTR2AKDM4EL3MBTL1 | |
| SCHEMBL14802083 | 0.72 | POLB (0.41) | LMNATAAR1HTR2AKDM4E | |
| Hydrochloric Acid SCHEMBL28421235 | 0.72 | CYP2C19 (0.44) | TAAR1HTR2AKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16144879 | 0.69 | MEN1 (0.42) | SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL193835 | 0.68 | HTR2A (0.52) | TRPA1HRH1LMNAGSRTAAR1 | |
| SCHEMBL1260 | 0.67 | TRPA1 (0.68) | TRPA1LMNATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937043-B1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2002-03-06 | — | — | EP | disclosed |
| EP-0937043-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998024765-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRIDIN DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-11 | — | — | WO | disclosed |