SCHEMBL7521769

SCHEMBL7521769

Cc1cc(C(F)C(F)(F)C(F)(F)F)cc(C)c1OS(=O)(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 2/20 0.39
P2RX7 Q99572 1/20 0.34
TDP1 Q9NUW8 4/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34
TUBB2B Q9BVA1 1/20 0.34
TUBB1 Q9H4B7 1/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPT P10636 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8501139 0.86 MEN1 (0.39) ALDH1A1GAALMNANPSR1SMN1; SMN2
SCHEMBL7454336 0.85 MAPT (0.42) ALPLTDP1ALDH1A1MAPTGAA
SCHEMBL7521765 0.80 ALPL (0.40) ALPLP2RX7TDP1TUBB4ATUBB
SCHEMBL3838741 0.79 ALPL (0.43) ALPLP2RX7TDP1TUBB4ATUBB
SCHEMBL19912237 0.79 ALPL (0.45) ALPLP2RX7TDP1TUBB4ATUBB
SCHEMBL8501897 0.76 ALPL (0.43) ALPLP2RX7TDP1TUBB4ATUBB
SCHEMBL28115946 0.75 FFAR4 (0.51) ALPLTDP1TUBB4ATUBBTUBA3C
SCHEMBL8501263 0.74 RAPGEF4 (0.37) ALDH1A1MAPTGAALMNASMN1; SMN2
SCHEMBL3838606 0.74 ALPL (0.46) ALPLP2RX7TDP1TUBB4ATUBB
SCHEMBL3842506 0.73 ALPL (0.45) ALPLP2RX7TDP1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020172652-A1 Composition for film formation and material for insulating film formation JSR CORPORATION (JP) 2002-11-21 US disclosed
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020172652-A1 Composition for film formation and material for insulating film formation VCL, BMI1, PUF60 ALPL 3061/4885P2RX7 4191/4885TDP1 1971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.