Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521809 | 1.00 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL7530541 | 0.82 | MAPT (0.59) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL9361815 | 0.82 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL8415313 | 0.78 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL28241832 | 0.78 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL9361903 | 0.78 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 | |
| SCHEMBL11263151 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL11263148 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL12288715 | 0.76 | ACHE (0.51) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL12838314 | 0.76 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1BACE1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892067-B1 | FLUORESCENT ENZYME SUBSTRATES AND METHOD FOR ASSAYING ENZYMATIC ACTIVITY | LAB MOLECULAR BIOPHOTONICS (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6207365-B1 | AN ENZYME SUBSTRATE WITH A CLEAVABLE CARBOXYL, PHOSPHORIC ACID, OR SULFURIC ACID GROUP WHICH UNDERGOES INTRAMOLECULAR LACTONIZATION TO FORM A STRONGLY FLUORESCENT COUMARIN DERIVATIVE; FOR DETECTING ENZYME ACTIVITY | LABORATORY OF MOLECULAR BIOPHOTONICS (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0892067-A1 | FLUORESCENT ENZYME SUBSTRATES AND METHOD FOR ASSAYING ENZYMATIC ACTIVITY | Laboratory of Molecular Biophotonics (JP) | 1999-01-20 | — | — | EP | disclosed |