SCHEMBL7521967

SCHEMBL7521967

CCCCNC(=O)ON1C(C)(C)CC(OC(=O)C(CC)(CC)C(=O)OC2CC(C)(C)N(OC(=O)NCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
BCHE P06276 2/20 0.38
ACHE P22303 9/20 0.36
TSHR P16473 2/20 0.34
KMT2A Q03164 2/20 0.34
EPHX1 P07099 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
SGPL1 O95470 1/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244099 0.80 ACHE (0.38) GAABCHEACHEKMT2AALDH1A1
SCHEMBL9440182 0.79 TSHR (0.52) GAATSHRKMT2AALDH1A1ESR1
SCHEMBL9247215 0.78 TSHR (0.50) GAABCHEACHETSHRKMT2A
SCHEMBL9242260 0.77 TSHR (0.64) GAABCHETSHRKMT2AALDH1A1
SCHEMBL9440168 0.77 ACHE (0.33) GAABCHEACHEEPHX1ALDH1A1
SCHEMBL19422677 0.77 GAA (0.49) GAABCHEACHEEPHX1ALDH1A1
SCHEMBL9247234 0.77 TSHR (0.54) GAABCHEACHETSHRKMT2A
SCHEMBL7521977 0.76 DPP8 (0.31) BCHEACHE
SCHEMBL11171093 0.76 UBE2M (0.33) GAAKMT2AMEN1
SCHEMBL27839355 0.75 ACHE (0.37) GAABCHEACHEEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
US-6500303-B1 DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL; PROTECTION FROM ULTRAVIOLET, FLUORESCENT AND SUN LIGHT EXPOSURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-31 US disclosed
US-20020124980-A1 Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives SELTZER RAYMOND R (US) 2002-09-12 US disclosed
US-6447644-B1 PULP OR PAPER THAT STILL CONTAINS LIGNIN, AND A STERICALLY HINDERED AMINE, FOR EXAMPLE DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-10 US disclosed
US-6254724-B1 STABILIZING AMOUNT OF A HINDERED AMINE COMPOUND SELECTED DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL OR WHICH ARE THEIR HYDROXYLAMINE SALTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-03 US disclosed
EP-0467849-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed