SCHEMBL9440168

SCHEMBL9440168

CCCCNC(=O)ON1C(C)(C)CC(C(CC(CC)(C(=O)O)C(=O)O)C2CC(C)(C)N(OC(=O)NCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.33
BCHE P06276 1/20 0.33
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
EPHX1 P07099 1/20 0.31
ALOX15 P16050 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737332 0.80 ACHE (0.35) ACHEBCHEALDH1A1GAAEPHX1
SCHEMBL7521967 0.77 GAA (0.38) ACHEBCHEALDH1A1GAAEPHX1
SCHEMBL7521977 0.77 DPP8 (0.31) ACHEBCHE
SCHEMBL11171095 0.77 UBE2M (0.34)
SCHEMBL27839355 0.76 ACHE (0.37) ACHEBCHEGAAEPHX1
SCHEMBL11179812 0.75 UBE2M (0.31)
SCHEMBL7509237 0.74 ALDH1A1 (0.31) ALDH1A1GAAALOX15
SCHEMBL11169057 0.74 TSHR (0.33)
SCHEMBL9737321 0.73 ACHE (0.35) ACHEBCHEALDH1A1GAAEPHX1
SCHEMBL9745430 0.72 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed