Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521985 | 0.78 | KMT2A (0.72) | ALDH1A1MEN1KMT2AGAAPKM | |
| SCHEMBL407668 | 0.77 | CA12 (0.61) | ALDH1A1CA12OPRK1 | |
| SCHEMBL7522527 | 0.76 | SETDB1 (0.51) | MEN1KMT2AGAAOPRK1 | |
| SCHEMBL16825009 | 0.76 | PKM (0.51) | ALDH1A1MEN1KMT2APKMHPGD | |
| SCHEMBL126986 | 0.74 | PKM (0.53) | ALDH1A1MEN1KMT2APKMCA12 | |
| SCHEMBL30194714 | 0.74 | PKM (0.53) | ALDH1A1MEN1KMT2APKMCA12 | |
| SCHEMBL25211050 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AGAAPKM | |
| SCHEMBL7200209 | 0.73 | PKM (0.51) | ALDH1A1PKMHPGDCA12TP53 | |
| SCHEMBL25241467 | 0.73 | CYP19A1 (0.50) | NR3C2 | |
| SCHEMBL4070788 | 0.72 | TSHR (0.49) | ALDH1A1KMT2APKMHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | claimed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | claimed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |