Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319620 | 0.90 | ALDH1A1 (0.47) | PKMNPSR1POLBMEN1KMT2A | |
| SCHEMBL581685 | 0.74 | PKM (0.42) | PKMNPSR1POLBMEN1KMT2A | |
| SCHEMBL3080016 | 0.74 | PKM (0.42) | PKMNPSR1POLBMEN1KMT2A | |
| SCHEMBL3073261 | 0.74 | PKM (0.42) | PKMNPSR1POLBMEN1KMT2A | |
| SCHEMBL581537 | 0.74 | POLB (0.46) | NPSR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9367156 | 0.73 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9171495 | 0.72 | ABL1 (0.47) | NPSR1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29965675 | 0.71 | MAPT (0.46) | PKMNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL18828659 | 0.69 | L3MBTL1 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6594587 | 0.69 | NPC1 (0.44) | PKMNPSR1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585328-B1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER (US) | 2002-01-09 | — | — | EP | disclosed |
| US-5852038-A | Substituted 3-aminoquinuclidines | PFIZER INC (US) | 1998-12-22 | — | — | US | disclosed |
| US-5716965-A | Substituted 3-aminoquinuclidines | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0585328-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020676-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1992-11-26 | — | — | WO | disclosed |