Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006378 | 0.84 | EPHX2 (0.49) | EPHX2NR1H4CYP2C9CYP2C19CA1 | |
| SCHEMBL3672272 | 0.82 | CYP2C9 (0.48) | CYP2C9CYP2C19CA1CA2TPSAB1 | |
| SCHEMBL11981491 | 0.81 | IDO1 (0.52) | CYP2C9CYP2C19CA1CA2IDO1 | |
| SCHEMBL28464230 | 0.80 | ALDH1A1 (0.41) | EPHX2NR1H4CYP2C9CYP2C19CA1 | |
| Hydrochloric Acid SCHEMBL28464115 | 0.79 | ALDH1A1 (0.39) | EPHX2NR1H4CYP2C9CYP2C19CA1 | |
| SCHEMBL18235899 | 0.78 | CYP2C9 (0.39) | EPHX2NR1H4CYP2C9CYP2C19CA1 | |
| SCHEMBL19361364 | 0.78 | LPL (0.42) | CYP2C9CYP2C19CA2TPSAB1ALDH1A1 | |
| SCHEMBL13879953 | 0.77 | CYP2C9 (0.41) | EPHX2NR1H4CYP2C9CYP2C19CA1 | |
| SCHEMBL16181585 | 0.77 | NOS1 (0.52) | EPHX2NR1H4CYP2C9CYP2C19CA1 | |
| SCHEMBL4100287 | 0.77 | IDO1 (0.52) | IDO1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |