Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579748 | 1.00 | ESR1 (0.56) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL11043870 | 0.88 | ESR1 (0.56) | ESR1CYP19A1MAOBRETKDR | |
| SCHEMBL5579742 | 0.88 | ESR1 (0.56) | ESR1CYP19A1MAOBRETKDR | |
| SCHEMBL11251156 | 0.78 | CYP19A1 (0.48) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL8702376 | 0.75 | ESR1 (0.45) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL9434848 | 0.75 | ESR1 (0.45) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL92288 | 0.75 | ESR1 (0.45) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL11383340 | 0.74 | CYP19A1 (0.44) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL31015940 | 0.73 | RET (0.41) | ESR1CYP19A1MAOBMEN1KMT2A | |
| SCHEMBL29209401 | 0.71 | CYP19A1 (0.41) | ESR1CYP19A1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| JP-2000198779-A | PURIFICATION OF 3-ALKYLFLAVANOL DERIVATIVE | KAO CORP | 2000-07-18 | — | — | JP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |