SCHEMBL7522504

SCHEMBL7522504

CCCCOc1c(OC)c(OC)cc(C)c1C(=O)c1c(C)cccc1OC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNB1 Q14721 2/20 0.42
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
TAS1R2 Q8TE23 1/20 0.42
KMT2A Q03164 3/20 0.41
PPARA Q07869 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
SLC6A5 Q9Y345 2/20 0.39
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520212 0.92 PPARA (0.43) KCNB1TAS1R3TAS1R1TAS1R2KMT2A
SCHEMBL7518830 0.90 L3MBTL1 (0.41) KCNB1KMT2APPARAL3MBTL1ALDH1A1
SCHEMBL6150070 0.87 L3MBTL1 (0.43) KCNB1KMT2AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL7523163 0.86 L3MBTL1 (0.40) KCNB1KMT2APPARAL3MBTL1MAPT
SCHEMBL6740389 0.86 KCNB1 (0.47) KCNB1TAS1R3TAS1R1TAS1R2KMT2A
SCHEMBL6740826 0.86 MEN1 (0.41) KMT2AL3MBTL1MEN1THRBSLC6A5
SCHEMBL7626410 0.85 KMT2A (0.43) KCNB1TAS1R3TAS1R1TAS1R2KMT2A
SCHEMBL6149703 0.84 L3MBTL1 (0.42) KMT2AL3MBTL1MAPTMEN1THRB
SCHEMBL6150124 0.83 L3MBTL1 (0.43) KMT2AL3MBTL1ALDH1A1SMN1; SMN2LMNA
SCHEMBL6150332 0.83 HPGD (0.41) KMT2AL3MBTL1MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US disclosed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed