SCHEMBL7518830

SCHEMBL7518830

CCCCOc1c(OC)c(OC)cc(C)c1C(=O)c1c(Cl)cccc1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.41
HPGD P15428 3/20 0.41
KCNB1 Q14721 1/20 0.40
MAPT P10636 4/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 3/20 0.40
GAA P10253 1/20 0.40
PPARA Q07869 1/20 0.39
NPC1 O15118 2/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523163 0.97 L3MBTL1 (0.40) L3MBTL1HPGDKCNB1MAPTMAPK1
SCHEMBL6150070 0.95 L3MBTL1 (0.43) L3MBTL1HPGDKCNB1MAPTMAPK1
SCHEMBL6149703 0.92 L3MBTL1 (0.42) L3MBTL1HPGDMAPTRAB9AGAA
SCHEMBL6150124 0.92 L3MBTL1 (0.43) L3MBTL1HPGDMAPTMAPK1RAB9A
SCHEMBL6150332 0.91 HPGD (0.41) L3MBTL1HPGDKMT2AMEN1
SCHEMBL6150736 0.91 HPGD (0.41) L3MBTL1HPGDKMT2AMEN1
SCHEMBL6149687 0.90 RAB9A (0.42) L3MBTL1HPGDKCNB1MAPTMAPK1
SCHEMBL7522504 0.90 KCNB1 (0.42) L3MBTL1KCNB1MAPTPPARAKMT2A
SCHEMBL7517866 0.87 KCNB1 (0.39) L3MBTL1HPGDKCNB1MAPTMAPK1
SCHEMBL6742658 0.87 KCNB1 (0.44) KCNB1MAPTRAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP claimed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US claimed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP claimed
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US disclosed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed