SCHEMBL6150124

SCHEMBL6150124

CCCCOc1c(OC)cc(C)c(C(=O)c2c(Cl)cccc2Cl)c1OCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.43
HPGD P15428 3/20 0.43
MAPT P10636 3/20 0.42
GAA P10253 2/20 0.42
RAB9A P51151 2/20 0.42
MAPK1 P28482 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SLC6A5 Q9Y345 2/20 0.39
PDE4B Q07343 2/20 0.38
PDE4A P27815 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
CXCL12 P48061 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
DPP4 P27487 1/20 0.38
KDM7A Q6ZMT4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150070 0.96 L3MBTL1 (0.43) L3MBTL1HPGDMAPTGAARAB9A
SCHEMBL6149703 0.93 L3MBTL1 (0.42) L3MBTL1HPGDMAPTGAARAB9A
SCHEMBL6150332 0.92 HPGD (0.41) L3MBTL1HPGDMEN1KMT2A
SCHEMBL6150736 0.92 HPGD (0.41) L3MBTL1HPGDMEN1KMT2A
SCHEMBL7518830 0.92 L3MBTL1 (0.41) L3MBTL1HPGDMAPTGAARAB9A
SCHEMBL6149687 0.91 RAB9A (0.42) L3MBTL1HPGDMAPTGAARAB9A
SCHEMBL7523163 0.89 L3MBTL1 (0.40) L3MBTL1HPGDMAPTGAARAB9A
SCHEMBL6150798 0.86 L3MBTL1 (0.44) L3MBTL1HPGDMAPTGAARAB9A
SCHEMBL6149532 0.85 TUBB4A (0.40) L3MBTL1MAPTGAARAB9ALMNA
SCHEMBL7522504 0.83 KCNB1 (0.42) L3MBTL1MAPTLMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727141-B1 Fungicidal methods, compounds and compositions containing benzophenones BASF AG (DE) 2005-11-02 EP claimed
EP-0727141-B1 Fungicidal methods, compounds and compositions containing benzophenones BASF AG (DE) 2005-11-02 EP disclosed
US-20020155518-A1 Method of detecting compounds that control fungal diseases via effects on sporulation BASF AKTIENGESELLSCHAFT (DE) 2002-10-24 US disclosed
US-5922919-A Fungicidal methods, compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
US-5866722-A Fungicidal methods compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-02-02 US disclosed
US-5773663-A FOR CONTROL OF PHYTOPATHOGENIC FUNGI IN CROPS AMERICAN CYANAMID COMPANY (US) 1998-06-30 US disclosed
US-5679866-A CONTROLLING POWDERY MELDEW DISEASES AMERICAN CYANAMID COMPANY (US) 1997-10-21 US disclosed
EP-0727141-A2 Fungicidal methods, compounds and compositions containing benzophenones American Cyanamid Company (US) 1996-08-21 EP disclosed