SCHEMBL75226

SCHEMBL75226

N#Cc1ccc2ccccc2n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.53
KCNH2 Q12809 1/20 0.53
NQO1 P15559 1/20 0.52
SOS2 Q07890 1/20 0.50
NCF1 P14598 3/20 0.46
CYP1A2 P05177 2/20 0.46
NOS2 P35228 1/20 0.46
BACE1 P56817 1/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 4/20 0.46
GAA P10253 1/20 0.46
TTR P02766 1/20 0.45
GLA P06280 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
ACHE P22303 1/20 0.42
MGAM O43451 1/20 0.41
SRC P12931 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359679 1.00 GRM5 (0.53) GRM5KCNH2NQO1SOS2NCF1
SCHEMBL27416745 1.00 GRM5 (0.53) GRM5KCNH2NQO1SOS2NCF1
Methane SCHEMBL27560165 0.98 GRM5 (0.52) GRM5KCNH2NQO1SOS2NCF1
Hydrochloric Acid SCHEMBL28328423 0.98 GRM5 (0.52) GRM5KCNH2NQO1SOS2NCF1
Hydrazine SCHEMBL28226443 0.96 GRM5 (0.50) GRM5KCNH2NQO1SOS2NCF1
Ethane SCHEMBL28069598 0.96 NQO1 (0.53) GRM5KCNH2NQO1SOS2NCF1
Ethylene SCHEMBL4594450 0.96 GRM5 (0.50) GRM5KCNH2NQO1SOS2NCF1
SCHEMBL15877631 0.89 GRM5 (0.62) GRM5KCNH2NQO1SOS2NCF1
Quinoline SCHEMBL28130812 0.89 ALDH1A1 (0.61) GRM5KCNH2NQO1SOS2NCF1
Pyrrole SCHEMBL28298992 0.89 GRM5 (0.45) GRM5KCNH2NQO1SOS2NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2732 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001858-A1 DEVICE SYSTEM AND METHOD FOR PREPARING CYCLIC CARBONATE BY DIOL ESTERIFYING CYCLIZATION HUIZHOU INSTITUTE OF GREEN ENERGY AND ADVANCED MAT (CN) 2026-01-01 US claimed
WO-2025107369-A1 APPARATUS SYSTEM AND METHOD FOR PREPARING CYCLIC CARBONATE BY CYCLOESTERIFICATION OF DIOL 惠州市绿色能源与新材料研究院 2025-05-30 WO claimed
CN-119462597-A Specific chemiluminescent probe for measuring CYP3A, preparation method and application thereof 遵义医科大学 2025-02-18 CN claimed
CN-117563512-B Device system and method for preparing cyclic carbonate through diol ring esterification 惠州市绿色能源与新材料研究院 2024-12-03 CN claimed
CN-118978522-A Synthesis method of 2-substituted-4-hydroxy-2-thiazoline derivative 信阳师范学院 2024-11-19 CN claimed
CN-118791462-A Construction and application of activated quinolinecarbonitrile aggregation-induced emission probe 华东理工大学 2024-10-18 CN claimed
CN-112710838-B Application of quinoline nitrile derivative in detection of protein by protein imprinting method and preparation method thereof 华东理工大学 2024-08-06 CN claimed
CN-118164953-A Asymmetric heptamethine quinoline cyanine fluorescent dye and application thereof 河北大学 2024-06-11 CN claimed
EP-3386511-B2 METHODS FOR TREATING HUNTINGTON'S DISEASE PTC THERAPEUTICS INC (US) 2024-03-20 EP claimed
CN-117563512-A Device system and method for preparing cyclic carbonate through diol ring esterification 惠州市绿色能源与新材料研究院 2024-02-20 CN claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5565408-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-10-15 US claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
EP-0459140-B1 Cyanoquinolines as herbicides BASF AG (DE) 1996-09-11 EP claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed