SCHEMBL7522869

SCHEMBL7522869

CN(CC(O)CO)C(=O)c1c(Br)c(NC(=O)CO)c(Br)c(C(N)=O)c1Br

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523494 0.87 LMNA (0.49) LMNA
SCHEMBL7527232 0.85 LMNA (0.59) LMNA
SCHEMBL8663593 0.84 LMNA (0.61) LMNA
SCHEMBL7529357 0.82 LMNA (0.64) LMNA
SCHEMBL7534524 0.79 LMNA (0.60) LMNA
SCHEMBL7522583 0.76 LMNA (0.64) LMNA
SCHEMBL13138908 0.76 LMNA (0.62) LMNA
SCHEMBL13885446 0.76 LMNA (0.65) LMNA
SCHEMBL7590464 0.75 LMNA (0.56) LMNA
SCHEMBL11291943 0.75 LMNA (0.51) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1186305-A1 New brominated compounds as contrast media for X-ray mammography Schering Aktiengesellschaft (DE) 2002-03-13 EP claimed
EP-1186305-A1 New brominated compounds as contrast media for X-ray mammography Schering Aktiengesellschaft (DE) 2002-03-13 EP disclosed