Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522869 | 0.87 | LMNA (0.44) | LMNA | |
| SCHEMBL7529357 | 0.83 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7530588 | 0.81 | LMNA (0.53) | LMNACYP2C19HIF1A | |
| SCHEMBL7522583 | 0.79 | LMNA (0.64) | LMNACYP2C19HIF1A | |
| SCHEMBL709499 | 0.77 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1CYP2C19HIF1A | |
| SCHEMBL13955980 | 0.76 | LMNA (0.66) | LMNAALDH1A1CYP2C19HIF1A | |
| SCHEMBL7534524 | 0.76 | LMNA (0.60) | LMNACYP2C19HIF1A | |
| SCHEMBL7526266 | 0.76 | PKM (0.39) | PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL14435477 | 0.76 | LMNA (0.48) | LMNAPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7530763 | 0.75 | LMNA (0.48) | LMNAPKMSMN1; SMN2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |