Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523406 | 0.91 | GRIK1 (0.54) | GRIK1GRIK2 | |
| SCHEMBL7465474 | 0.84 | P2RY12 (0.47) | — | |
| SCHEMBL7466216 | 0.77 | P2RY12 (0.47) | — | |
| SCHEMBL7463645 | 0.75 | GRIK1 (0.54) | GRIK1 | |
| SCHEMBL7531464 | 0.75 | GRIK1 (0.56) | GRIK1 | |
| SCHEMBL7528058 | 0.73 | FLT1 (0.61) | GRIK1 | |
| SCHEMBL10401308 | 0.72 | SMN1; SMN2 (0.57) | GRIK1 | |
| SCHEMBL7522905 | 0.71 | GRIK1 (0.50) | GRIK1 | |
| SCHEMBL7559587 | 0.71 | GRIK1 (0.66) | GRIK1 | |
| SCHEMBL8960506 | 0.69 | VCAM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |