SCHEMBL7522914

SCHEMBL7522914

CC(=O)OC1=C(c2ccccc2)C2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.40
TDP1 Q9NUW8 2/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 4/20 0.37
GAA P10253 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ELANE P08246 1/20 0.37
ESR1 P03372 1/20 0.37
ITGB3 P05106 1/20 0.37
ITGA2B P08514 1/20 0.37
HMGB1 P09429 1/20 0.37
HPGD P15428 1/20 0.37
GGT1 P19440 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
BLM P54132 1/20 0.37
NAPRT Q6XQN6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9354923 0.87 LMNA (0.38) MAPTLMNAKDM4EHPGDSLC6A3
SCHEMBL31376343 0.79 NLRP3 (0.37) TDP1MAPTLMNAGAAALDH1A1
SCHEMBL11533876 0.75 ALDH1A1 (0.46) TDP1LMNAALDH1A1TSHRELANE
SCHEMBL9617145 0.74 KMT2A (0.30)
SCHEMBL7117273 0.73 ALDH1A1 (0.40) LMNAALDH1A1HSD17B10SLC6A3CYP1A2
SCHEMBL9354912 0.73 LMNA (0.42) MAPTLMNAALDH1A1TSHRHPGD
SCHEMBL11527406 0.68 HTT (0.51) BACE1TDP1MAPTGAAALDH1A1
SCHEMBL12708408 0.68 HTT (0.51) BACE1TDP1MAPTGAAALDH1A1
SCHEMBL2705383 0.66 KDM4E (0.42) TDP1MAPTLMNAGAAALDH1A1
SCHEMBL12096096 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845483-B1 Fluorine-containing copolymer having rings on its main chain ASAHI GLASS CO LTD (JP) 2002-03-13 EP disclosed
US-5962612-A POWDER COATING ASAHI GLASS COMPANY LTD. (JP) 1999-10-05 US disclosed
EP-0845483-A1 Fluorine-containing copolymer having rings on its main chain ASAHI GLASS COMPANY LTD. (JP) 1998-06-03 EP disclosed