Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP24A1 | Q07973 | 4/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528414 | 0.90 | HSD17B10 (0.52) | ALOX15TSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL7522620 | 0.86 | HSD17B10 (0.51) | ALOX15TSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL7401506 | 0.86 | AOC3 (0.44) | HSD17B10ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL227895 | 0.81 | MAOB (0.61) | ITGB3ITGA2BALDH1A1CYP24A1MAOA | |
| SCHEMBL13193349 | 0.80 | THRA (0.62) | MAPTL3MBTL1ALDH1A1CYP24A1CYP26A1 | |
| SCHEMBL7389120 | 0.79 | HSD17B10 (0.62) | ALOX15TSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL31711410 | 0.79 | HSD17B10 (0.62) | ALOX15TSHRHSD17B10MAPTL3MBTL1 | |
| SCHEMBL7962734 | 0.78 | SMN1; SMN2 (0.48) | ITGB3ITGA2BCYP24A1CYP26A1CYP27A1 | |
| SCHEMBL2440274 | 0.77 | CYP24A1 (0.56) | CYP24A1CYP26A1CYP27A1ACHECYP19A1 | |
| SCHEMBL7520647 | 0.76 | ALOX15 (0.68) | ALOX15TSHRHSD17B10MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417213-B2 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| US-20020006944-A1 | Tricyclic compounds, their production and use | OHKAWA SHIGENORI (JP) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006944-A1 | Tricyclic compounds, their production and use | CNR1, PTGER1, PTGDR | ALOX15 448/4885TSHR 179/4885HSD17B10 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.