Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.36 |
| ▸ | TK1 | P04183 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502919 | 0.84 | TK1 (0.42) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL7514211 | 0.84 | TK1 (0.42) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL4924705 | 0.79 | KIF11 (0.59) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL4924692 | 0.79 | KIF11 (0.59) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL4931427 | 0.79 | KIF11 (0.59) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL27997026 | 0.78 | KIF11 (0.57) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL2108370 | 0.76 | THRB (0.46) | CYP2C19ALDH1A1PPARG | |
| SCHEMBL4533570 | 0.75 | KIF11 (0.53) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL6749203 | 0.75 | KIF11 (0.53) | KIF11TSHRCYP2C19CYP2C9ALOX15 | |
| SCHEMBL5899878 | 0.75 | KIF11 (0.53) | KIF11TSHRCYP2C19CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173397-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-Sipsy S.C.A. (FR) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066519-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-SIPSY S.C.A. (FR) | 2000-11-09 | — | — | WO | disclosed |