SCHEMBL752325

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10412134	0.89	KMT2A (0.55)	ALDH1A1L3MBTL1KMT2APABPC1PKM
	SCHEMBL752911	0.82	ALDH1A1 (0.57)	KDM1AALDH1A1L3MBTL1KMT2APKM
	SCHEMBL13740053	0.80	ALDH1A1 (0.47)	KDM1AALDH1A1KMT2APABPC1HSD17B10
	SCHEMBL754182	0.80	KDM4E (0.63)	KDM1AALDH1A1L3MBTL1KMT2AHSD17B10
	SCHEMBL29372620	0.76	EGFR (0.54)	ALDH1A1L3MBTL1HSD17B10CYP2C19KDM4E
	SCHEMBL10669287	0.76	ALDH1A1 (0.54)	ALDH1A1L3MBTL1KMT2AHSD17B10KDM4E
	SCHEMBL14236771	0.75	ALDH1A1 (0.50)	KDM1AALDH1A1L3MBTL1KMT2APABPC1
	SCHEMBL14577313	0.74	PABPC1 (0.59)	ALDH1A1KMT2APABPC1PKMEIF4H
	SCHEMBL1092586	0.74	KDM4E (0.67)	ALDH1A1L3MBTL1KMT2APABPC1PKM
	SCHEMBL5001736	0.74	ALDH1A1 (0.54)	ALDH1A1L3MBTL1KMT2APKMHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.