SCHEMBL754182

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5001736	0.88	ALDH1A1 (0.54)	KDM4EALDH1A1CYP2C19HSD17B10HTT
	SCHEMBL29372620	0.80	EGFR (0.54)	KDM4EALDH1A1CYP2C19HSD17B10HTT
	SCHEMBL752325	0.80	KDM1A (0.51)	KDM4EALDH1A1CYP2C19HSD17B10HTT
	SCHEMBL11811603	0.77	EGFR (0.65)	KDM4EALDH1A1HTTMAPTSMN1; SMN2
	SCHEMBL30639179	0.77	KDM4E (0.67)	KDM4EALDH1A1MAPTKMT2AEGFR
	SCHEMBL1092586	0.77	KDM4E (0.67)	KDM4EALDH1A1MAPTKMT2AEGFR
	SCHEMBL8689614	0.76	KDM4E (0.50)	KDM4EMAPTKMT2AEGFRL3MBTL1
	SCHEMBL7482958	0.76	MCL1 (0.52)	KDM4EALDH1A1HTTMAPTKMT2A
	SCHEMBL2662567	0.76	EGFR (0.54)	KDM4EALDH1A1HSD17B10HPGDMAPT
	SCHEMBL27967619	0.76	KDM4E (0.52)	KDM4EALDH1A1HPGDMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.