Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526616 | 0.80 | VCAM1 (0.38) | VCAM1NPSR1KDM4EMEN1RECQL | |
| SCHEMBL7516417 | 0.73 | VCAM1 (0.37) | VCAM1NPSR1KDM4EMEN1RECQL | |
| SCHEMBL27670207 | 0.70 | TDP1 (0.55) | VCAM1NPSR1KDM4EMEN1RECQL | |
| SCHEMBL7517750 | 0.69 | KDM4E (0.33) | KDM4EPTGDR2 | |
| SCHEMBL7524936 | 0.68 | VCAM1 (0.40) | VCAM1NPSR1MEN1KMT2ARBP4 | |
| SCHEMBL18998964 | 0.67 | VCAM1 (0.47) | VCAM1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL7516065 | 0.65 | VCAM1 (0.39) | VCAM1NPSR1KDM4EMEN1RECQL | |
| SCHEMBL7515913 | 0.65 | VCAM1 (0.43) | VCAM1RBP4PTGDR2 | |
| SCHEMBL7525872 | 0.65 | VCAM1 (0.36) | VCAM1NPSR1KDM4ERBP4PTGDR2 | |
| SCHEMBL3551020 | 0.64 | KDM4E (0.50) | NPSR1KDM4EMEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |