Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522056 | 0.88 | KDM4E (0.34) | PTGDR2SLC6A9KDM4EGAAMAPK1 | |
| SCHEMBL7518926 | 0.86 | SLC6A9 (0.33) | PTGDR2SLC6A9KDM4EGAAMAPK1 | |
| SCHEMBL7518758 | 0.84 | VCAM1 (0.47) | VCAM1LTB4RRXRARXRBKCNH2 | |
| SCHEMBL7520154 | 0.80 | ALOX15 (0.43) | KDM4EGAAMAPK1ALDH1A1 | |
| SCHEMBL7524936 | 0.77 | VCAM1 (0.40) | VCAM1PTGDR2RBP4NPSR1 | |
| SCHEMBL7517609 | 0.76 | VCAM1 (0.45) | VCAM1LTB4RGAAMAPK1ALDH1A1 | |
| SCHEMBL7524217 | 0.75 | VCAM1 (0.37) | VCAM1KDM4EGAAALDH1A1L3MBTL1 | |
| SCHEMBL7516405 | 0.74 | KDM4E (0.40) | PTGDR2KDM4EGAAMAPK1RXRA | |
| SCHEMBL6054926 | 0.73 | VCAM1 (0.51) | VCAM1GAAALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL7523688 | 0.72 | VCAM1 (0.35) | VCAM1KDM4EGAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |