Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523714 | 0.81 | HTT (0.32) | NPC1KMT2AKDM4E | |
| SCHEMBL8138655 | 0.73 | CACNA1B (0.35) | DRD3NPC1POLBRAD52RAB9A | |
| SCHEMBL5264237 | 0.73 | CYP1A2 (0.41) | NPC1POLBRAB9AKMT2AKDM4E | |
| SCHEMBL7263829 | 0.71 | SIRT2 (0.38) | NPC1KMT2AKDM4E | |
| SCHEMBL7119512 | 0.71 | KDM1A (0.39) | SLC2A1KMT2AKDM1A | |
| SCHEMBL361847 | 0.70 | KDM4E (0.50) | NPC1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL8127106 | 0.69 | TOP2A (0.33) | TOP2ADRD3NPC1POLBSLC2A1 | |
| SCHEMBL8137464 | 0.69 | RAD52 (0.36) | NPC1POLBRAD52RAB9AKMT2A | |
| SCHEMBL7971753 | 0.69 | HTT (0.36) | NPC1KMT2AKDM4E | |
| SCHEMBL7528809 | 0.69 | RAD52 (0.39) | TOP2ANPC1POLBSLC2A1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037885-B1 | NOVEL WATER SOLUBLE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1037885-B1 | NOVEL WATER SOLUBLE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2002-03-27 | — | — | EP | disclosed |