Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7519436 | 0.93 | MAPT (0.47) | MAPTALDH1A1LMNAHTTCYP2C19 | |
| SCHEMBL7523742 | 0.81 | KMT2A (0.38) | MAPTALDH1A1LMNAHTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL7519432 | 0.80 | KMT2A (0.36) | MAPTALDH1A1LMNAHTTGAA | |
| SCHEMBL7523739 | 0.74 | RAB9A (0.38) | MAPTALDH1A1LMNAHTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL7519429 | 0.72 | MEN1 (0.37) | MAPTALDH1A1LMNAHTTCYP2C19 | |
| SCHEMBL4557464 | 0.72 | MAPT (0.44) | MAPTALDH1A1LMNAHTTHPGD | |
| SCHEMBL5853815 | 0.71 | KMT2A (0.51) | MAPTALDH1A1LMNAHTTGAA | |
| SCHEMBL19858933 | 0.70 | KMT2A (0.50) | MAPTALDH1A1LMNAHTTGAA | |
| SCHEMBL6602157 | 0.70 | CYP2C19 (0.56) | ALDH1A1LMNAHTTCYP2C19GAA | |
| SCHEMBL10826149 | 0.69 | MAPT (0.45) | MAPTALDH1A1LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257538-A2 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060801-A2 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2001-08-23 | — | — | WO | disclosed |