Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7519432 | 0.87 | KMT2A (0.36) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL7523743 | 0.81 | MAPT (0.46) | KMT2AMEN1RAB9AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL7519436 | 0.78 | MAPT (0.47) | KMT2AMEN1MAPTLMNAGAA | |
| SCHEMBL7523739 | 0.73 | RAB9A (0.38) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL4557465 | 0.72 | CDK5 (0.37) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL5853815 | 0.72 | KMT2A (0.51) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7519429 | 0.71 | MEN1 (0.37) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL19858933 | 0.70 | KMT2A (0.50) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL7716965 | 0.70 | KMT2A (0.54) | KMT2AMEN1RAB9AMAPTL3MBTL1 | |
| SCHEMBL11644580 | 0.68 | ALDH1A1 (0.38) | KMT2AMEN1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257538-A2 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060801-A2 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2001-08-23 | — | — | WO | disclosed |