SCHEMBL7523780

SCHEMBL7523780

COC(=O)CCON1C(C)(C)CC(OCc2ccccc2)CC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.41
GAA P10253 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
TMEM97 Q5BJF2 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
EPHX2 P34913 1/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
LTA4H P09960 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7520600 0.94 KMT2A (0.39) TSHRKMT2AMEN1GAAKDM4E
SCHEMBL9243820 0.84 TSHR (0.48) TSHRKMT2AMEN1GAAALDH1A1
SCHEMBL9335197 0.82 CARM1 (0.42) TSHRKMT2AALDH1A1TMEM97CARM1
SCHEMBL9440082 0.82 CARM1 (0.46) TSHRKMT2AALDH1A1TMEM97CARM1
SCHEMBL9371206 0.81 TSHR (0.62) TSHRKMT2AMEN1GAAALDH1A1
SCHEMBL7475314 0.81 CARM1 (0.45) TSHRKMT2AALDH1A1TMEM97CARM1
SCHEMBL10430891 0.80 TSHR (0.64) TSHRKMT2AMEN1GAAKDM4E
SCHEMBL9240294 0.79 CARM1 (0.44) TSHRKMT2AALDH1A1TMEM97CARM1
Acetic Acid SCHEMBL3797025 0.79 TSHR (0.46) TSHRKMT2AMEN1GAAKDM4E
SCHEMBL7475800 0.77 TSHR (0.53) TSHRKMT2AMEN1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467850-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1995-09-06 EP claimed
EP-0389422-B1 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-5258138-A Phenothiazine and a 2,2,6,6-tetraalkyl piperazin-4-yl derivative to prevent addition polymerization of a mixture of acrylic monomers including an hydroxyalkyl acrylic ester; colorless CIBA-GEIGY CORPORATION (US) 1993-11-02 US claimed
EP-0467851-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
EP-0467850-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
US-5015678-A Light stabilized polymers by the addition of N-hydoxyamines CIBA-GEIGY CORPORATION (US) 1991-05-14 US claimed
EP-0389422-A2 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
JP-2286658-A None JP disclosed
US-6500303-B1 DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL; PROTECTION FROM ULTRAVIOLET, FLUORESCENT AND SUN LIGHT EXPOSURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-31 US disclosed
US-20020124980-A1 Inhibition of pulp and paper yellowing using nitroxides, hydroxylamines and other coadditives SELTZER RAYMOND R (US) 2002-09-12 US disclosed
US-6447644-B1 PULP OR PAPER THAT STILL CONTAINS LIGNIN, AND A STERICALLY HINDERED AMINE, FOR EXAMPLE DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-10 US disclosed
US-6254724-B1 STABILIZING AMOUNT OF A HINDERED AMINE COMPOUND SELECTED DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL OR WHICH ARE THEIR HYDROXYLAMINE SALTS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-03 US disclosed
EP-1000032-A1 INHIBITION OF PULP AND PAPER YELLOWING USING NITROXIDES AND OTHER COADDITIVES Ciba SC Holding AG (CH) 2000-05-17 EP disclosed
EP-0467850-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1995-09-06 EP disclosed
EP-0389422-B1 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
EP-0467851-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
EP-0467850-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
US-5015678-A Light stabilized polymers by the addition of N-hydoxyamines CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed
JP-H02286658-A STABILIZER DERIVED FROM N-HYDROXY HINDERED AMINE BY MICHAEL ADDITION REACTION CIBA GEIGY AG 1990-11-26 JP disclosed
EP-0389422-A2 Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed