Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HINT1 | P49773 | 7/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519312 | 0.82 | P2RX3 (0.36) | — | |
| SCHEMBL7518632 | 0.79 | POLB (0.31) | POLB | |
| SCHEMBL17279160 | 0.79 | KDM4E (0.49) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL8667140 | 0.79 | KDM4E (0.49) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL22702575 | 0.79 | KDM4E (0.49) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL17231771 | 0.79 | KDM4E (0.49) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL7529817 | 0.77 | TAAR1 (0.35) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL3485699 | 0.77 | HINT1 (0.49) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL5408372 | 0.76 | TYMP (0.37) | TAAR1HINT1TAS1R3TAS1R1POLB | |
| SCHEMBL17597173 | 0.74 | POLB (0.56) | HINT1POLBKDM4EGSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882059-B1 | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES | LYNX THERAPEUTICS INC (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0882059-A1 | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES | LYNX THERAPEUTICS, INC. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997031009-A1 | SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3'→P5' PHOSPHORAMIDATES | LYNX THERAPEUTICS, INC. (US) | 1997-08-28 | — | — | WO | disclosed |