SCHEMBL7518632

SCHEMBL7518632

CC(C)N(C(C)C)P(OCCC#N)OC(OC(=O)c1ccccc1)[C@H]1O[C@@H](n2ccc(N)nc2=O)C[C@@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.31
POLG P54098 1/20 0.30
ST6GAL1 P15907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7519312 0.86 P2RX3 (0.36)
SCHEMBL7520075 0.82 ST6GAL1 (0.33) ST6GAL1
SCHEMBL7523781 0.79 TAAR1 (0.37) POLB
SCHEMBL17279161 0.78 POLB (0.47) POLBST6GAL1
SCHEMBL22702494 0.78 POLB (0.47) POLBST6GAL1
SCHEMBL8667158 0.78 POLB (0.47) POLBST6GAL1
SCHEMBL17231769 0.78 POLB (0.47) POLBST6GAL1
SCHEMBL5488005 0.77 POLB (0.39) POLBPOLGST6GAL1
SCHEMBL2056493 0.75
SCHEMBL5396749 0.75 POLB (0.31) POLBST6GAL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882059-B1 SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDE N3-'P5'- PHOSPHORAMIDATES LYNX THERAPEUTICS INC (US) 2002-02-06 EP disclosed