Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11924487 | 0.82 | CHRNB2 (0.52) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL3558191 | 0.80 | ACHE (0.36) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL5031468 | 0.80 | CHRNB2 (0.50) | ACHECHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL24735973 | 0.80 | ACHE (0.41) | ACHECHRNB2CHRNA4 | |
| SCHEMBL28538773 | 0.80 | ACHE (0.36) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL12487443 | 0.78 | ACHE (0.35) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL31075623 | 0.77 | CHRNB2 (0.53) | ACHECHRNB2CHRNA4 | |
| SCHEMBL22898364 | 0.77 | ACHE (0.38) | ACHECHRNB2CHRNA4 | |
| Hydrazine SCHEMBL5719663 | 0.77 | ACHE (0.34) | ACHECHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL9593433 | 0.77 | EGLN1 (0.41) | ACHELMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016314-A1 | SUBSTITUTED POLYAMINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2002-02-28 | — | — | WO | disclosed |
| EP-0802955-B1 | A MARKING COMPOSITION | COLLER MIRIAM (US) | 2002-02-13 | — | — | EP | disclosed |