Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155814 | 0.84 | TSHR (0.75) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL12858908 | 0.83 | KDM4E (0.64) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL11239580 | 0.82 | TSHR (0.73) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL15296754 | 0.82 | CYP2C9 (0.57) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL11481090 | 0.82 | TSHR (0.68) | ALDH1A1CYP2D6KDM4ELMNAGAA | |
| SCHEMBL14355271 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL29201698 | 0.81 | LMNA (0.58) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL29201720 | 0.81 | LMNA (0.58) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL12781846 | 0.81 | KDM4E (0.66) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL7269243 | 0.81 | KDM4E (0.66) | SMN1; SMN2CYP2C9ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832079-B1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO FEJLESZTOE KFT (HU) | 2002-03-27 | — | — | EP | disclosed |
| US-6002002-A | Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions | BIOREX RESEARCH & DEVELOPMENT CO. (HU) | 1999-12-14 | — | — | US | disclosed |
| EP-0832079-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000251-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 1997-01-03 | — | — | WO | disclosed |