SCHEMBL7523966

SCHEMBL7523966

CCCC1CCC(CCC(O)CO)CC1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
LMNA P02545 4/20 0.34
MAPT P10636 2/20 0.34
USP2 O75604 1/20 0.33
CYP2C9 P11712 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CHEK2 O96017 1/20 0.32
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CYP1A2 P05177 1/20 0.31
HTT P42858 1/20 0.31
FYN P06241 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2952373 0.89
SCHEMBL9406978 0.81 LMNA (0.37) LMNAMAPTCYP2C9ALDH1A1MAPK1
SCHEMBL9406976 0.81 LMNA (0.37) LMNAMAPTCYP2C9ALDH1A1MAPK1
SCHEMBL11739573 0.80 METAP1 (0.42) THRBLMNAMAPTALDH1A1CYP1A2
SCHEMBL24370624 0.80 THRB (0.34) THRB
SCHEMBL9057114 0.80 TLR4 (0.36) LMNAMAPTCYP2C9ALDH1A1MAPK1
SCHEMBL9057108 0.80 TLR4 (0.36) LMNAMAPTCYP2C9ALDH1A1MAPK1
SCHEMBL9057106 0.80 TLR4 (0.36) LMNAMAPTCYP2C9ALDH1A1MAPK1
SCHEMBL1111381 0.78 METAP1 (0.46) THRBLMNAALDH1A1CYP1A2
SCHEMBL1678958 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020015804-A1 LIQUID-CRYSTAL COMPOUNDS, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT CONTAINING THE SAME CHISSO CORPORATION (JP) 2002-02-07 US disclosed
EP-0976703-A1 LIQUID-CRYSTAL COMPOUNDS, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT CONTAINING THE SAME CHISSO CORPORATION (JP) 2000-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020015804-A1 LIQUID-CRYSTAL COMPOUNDS, LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME, AND LIQUID-CRYSTAL DISPLAY ELEMENT CONTAINING THE SAME CXCR1, CCR1, CXCR2 THRB 3299/4885LMNA 3295/4885MAPT 3043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.