SCHEMBL7524124

SCHEMBL7524124

CC(C)(C)CC(C)(C)c1cc(/N=N/c2ccc(C(F)(F)F)cc2[N+](=O)[O-])c(O)c(C(C)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
ALDH1A1 P00352 4/20 0.44
GAA P10253 2/20 0.44
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
KCNMA1 Q12791 1/20 0.36
MITF O75030 1/20 0.36
HPGD P15428 1/20 0.36
MC4R P32245 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 2/20 0.35
AKR1B1 P15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6860822 0.93 MAPT (0.44) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL6868079 0.93 MAPT (0.44) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL7524129 0.88 MAPT (0.42) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL10385275 0.84 GPR35 (0.41) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL10385273 0.84 GPR35 (0.41) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL6864712 0.81 ALDH1A1 (0.36) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL6864708 0.81 ALDH1A1 (0.36) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL6865301 0.81 MAPT (0.51) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL6865307 0.81 MAPT (0.51) MAPTALDH1A1GAAMAPK1KDM4E
SCHEMBL29809621 0.81 CES2 (0.39) MAPTKMT2AMEN1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6489383-B1 SUCH AS 2-(2-HYDROXY-3-(1,1-DI(4-2-(BROMOETHOXY)PHENYL) ETHYL)-5-TERT-BUTYLPHENYL)-2H-BENZOTRIAZOLE FOR USE AS STOVING LACQUER, FINISHING ENAMEL FOR AUTOMOBILES CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-03 US disclosed
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith WOOD MERVIN G (US) 2002-11-14 US disclosed
US-6392056-B1 FOR THERMOPLASTIC RESINS CIBA SPECIALTY CHEMICAL CORPORATION 2002-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith SUV39H1, SUV39H2, PAH MAPT 287/4885ALDH1A1 85/4885GAA 2938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.