Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009986 | 0.87 | PTPN1 (0.42) | MAPK1PTPN1HSD17B10 | |
| SCHEMBL2009984 | 0.87 | PTPN1 (0.42) | MAPK1PTPN1HSD17B10 | |
| SCHEMBL201027 | 0.83 | MMP2 (0.41) | PTPN1MMP1MMP3MMP7MMP13 | |
| SCHEMBL22648657 | 0.83 | MMP2 (0.41) | PTPN1MMP1MMP3MMP7MMP13 | |
| SCHEMBL2534501 | 0.82 | NR1D1 (0.32) | — | |
| SCHEMBL12330397 | 0.81 | ELANE (0.36) | MAPK1PTPN1HRH3 | |
| SCHEMBL18089593 | 0.78 | PTPN1 (0.51) | PTPN1HSD17B10MMP1MMP3MMP7 | |
| SCHEMBL2531159 | 0.78 | PTPN1 (0.51) | PTPN1HSD17B10MMP1MMP3MMP7 | |
| SCHEMBL206327 | 0.78 | PTPN1 (0.51) | PTPN1HSD17B10MMP1MMP3MMP7 | |
| SCHEMBL206317 | 0.77 | HSD17B10 (0.42) | PTPN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |