SCHEMBL752439

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Acipimox SCHEMBL48922	0.74	HCAR2 (1.00)	HCAR2P4HTMKDM4EALDH1A1LMNA
	SCHEMBL12442577	0.74	HCAR2 (0.73)	HCAR2ALDH1A1
	Acipimox SCHEMBL29370131	0.74	HCAR2 (1.00)	HCAR2P4HTMKDM4EALDH1A1LMNA
	Acipimox SCHEMBL6057382	0.74	HCAR2 (1.00)	HCAR2P4HTMKDM4EALDH1A1LMNA
	SCHEMBL5655820	0.73	KDM4E (0.56)	NPC1RXFP1LTA4HRAB9ASMN1; SMN2
	SCHEMBL756842	0.73	NPC1 (0.60)	NPC1RXFP1LTA4HRAB9ASMN1; SMN2
	Acipimox SCHEMBL31290731	0.73	HCAR2 (0.96)	HCAR2P4HTMKDM4EALDH1A1LMNA
	Acipimox SCHEMBL28681646	0.73	HCAR2 (0.96)	HCAR2P4HTMKDM4EALDH1A1LMNA
	SCHEMBL5883522	0.73	HCAR2 (0.71)	HCAR2LMNA
	Acipimox SCHEMBL28986974	0.73	HCAR2 (0.96)	HCAR2P4HTMKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.