SCHEMBL756842

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2882776	0.82	NPC1 (0.59)	NPC1SMN1; SMN2RAB9AALDH1A1GAA
	SCHEMBL5655820	0.79	KDM4E (0.56)	NPC1SMN1; SMN2RAB9AALDH1A1GAA
	SCHEMBL7493215	0.79	POLB (0.52)	NPC1SMN1; SMN2RAB9AALDH1A1GAA
	SCHEMBL14734049	0.76	SMN1; SMN2 (1.00)	NPC1SMN1; SMN2RAB9AALDH1A1GAA
	SCHEMBL20474681	0.74	NPC1 (0.47)	NPC1SMN1; SMN2RAB9ARXFP1LTA4H
	SCHEMBL11252994	0.74	LTA4H (0.56)	NPC1SMN1; SMN2RAB9AALDH1A1RXFP1
	SCHEMBL754612	0.73	MAOB (0.40)	NPC1SMN1; SMN2RAB9AALDH1A1GAA
	SCHEMBL752439	0.73	HCAR2 (0.58)	NPC1SMN1; SMN2RAB9AALDH1A1GAA
	SCHEMBL5655331	0.72	LTC4S (0.53)	NPC1SMN1; SMN2RAB9ARXFP1LTA4H
	SCHEMBL27296576	0.72	KDM4E (0.55)	NPC1SMN1; SMN2RAB9AALDH1A1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.