Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.57 |
| ▸ | ITGAL | P20701 | 5/20 | 0.57 |
| ▸ | ACE | P12821 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28982976 | 0.86 | ALOX15 (0.64) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL3082097 | 0.83 | ALOX15 (0.57) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL3082092 | 0.83 | ALOX15 (0.57) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL15592745 | 0.81 | ACE (0.70) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL16750046 | 0.81 | ACE (0.70) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL1263833 | 0.81 | KDM4E (0.72) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL1263822 | 0.81 | KDM4E (0.72) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL19737124 | 0.81 | ACE (0.70) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL1131418 | 0.81 | ALOX15 (0.67) | ALOX15ITGB2ICAM1ITGALACE | |
| SCHEMBL1131419 | 0.81 | ALOX15 (0.67) | ALOX15ITGB2ICAM1ITGALACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981953-B | Polypeptide, application of polypeptide and composition containing polypeptide | 首都医科大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-110981953-A | Polypeptide, application of polypeptide and composition containing polypeptide | 首都医科大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-1137134-C | Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors | ���µ�˹ҩ�﹫˾ | 2004-02-04 | — | — | CN | disclosed |
| CN-1137134-C | Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors | ���µ�˹ҩ�﹫˾ | 2004-02-04 | — | — | CN | disclosed |
| EP-0863916-B1 | POLYFLUOROALKYL TRYPTOPHAN TRIPEPTIDE THROMBIN INHIBITORS | AVENTIS PHARMA INC (US) | 2002-04-10 | — | — | EP | disclosed |
| US-6069232-A | ANTICOAGULANTS FOR THERAPY AND PROPHYLAXIS OF CARDIOVASCULAR DISEASES, AND FOR STORAGE OF BLOOD | HOECHST MARION ROUSSEL, INC. (US) | 2000-05-30 | — | — | US | disclosed |
| CN-1198748-A | Polyfluoroalkyl tryptophan tripeptide thrombin inhibitors | HOECHST MARION ROUSSEL INC (US) | 1998-11-11 | — | — | CN | disclosed |
| EP-0863916-A1 | POLYFLUOROALKYL TRYPTOPHAN TRIPEPTIDE THROMBIN INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997012904-A1 | POLYFLUOROALKYL TRYPTOPHAN TRIPEPTIDE THROMBIN INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1997-04-10 | — | — | WO | disclosed |